Cytotoxic effects of Curcuma longa leaves on MCF-7 and HepG2 cells

Curcuma longa (tumeric) is listed in several therapeutic regimens used the management of cancer. The present study investigated potential cytotoxic effects ethanol extract (turmeric) leaves on HepG2 (a human hepatocellular carcinoma cell line), and MCF-7 mammary gland adenocarcinoma line) cells. cells were exposed to different concentrations; 2, 0.2, 0.02, 0.002, 0.0002, 0.00002, 0.000002 μg/ml, C. leaves. Water-Soluble tetrazolium salt (WST-1) assay was estimate viability after which percentage proliferation computed. results this indicated that had effect lines, caused a decrease it more selective breast cancer lines based WST-1 analysis These suggest leaf possesses properties, can be exploited develop novel drugs for management. Keywords: longa, turmeric, HepG2, MCF-7, WST-1, proliferation, cytotoxic,